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A Futuristic Development in 3D Printing Technique Using Nanomaterials with a Step Toward 4D Printing
Prachi Agarwal1, Vidhi Mathur1, Meghana Kasturi2
1Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Karnataka, Manipal 576104, India.
ACS Omega
|September 16, 2024
Summary
3D bioprinting, enhanced by nanotechnology, creates advanced tissue scaffolds. Emerging 4D bioprinting techniques enable dynamic tissue structures for regenerative medicine applications.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Nanotechnology
Background:
- 3D bioprinting offers precise fabrication of patient-specific tissue scaffolds and medical devices.
- Nanomaterials and nanotechnology enhance 3D bioprinted scaffolds with unique properties.
- These advancements improve the clinical efficacy of engineered tissues.
Purpose of the Study:
- To explore the impact of nanotechnology and nanomaterials on 3D bioprinted tissue scaffolds.
- To discuss the principles and potential of 4D bioprinting in creating dynamic tissue architectures.
- To highlight the future applications of 4D bioprinting in biomedical technologies.
Main Methods:
- Integration of nanomaterials and nanotechnology into 3D bioprinting processes.
- Development of stimuli-responsive biomaterials and cells for 4D bioprinting.
- Analysis of morphological changes in tissue architecture using dynamic designs.
Main Results:
- Nanomaterials impart improved physicochemical and biological properties to 3D bioprinted scaffolds.
- Nanotechnology enhances the performance of tissue engineered scaffolds for regenerative medicine.
- 4D bioprinting enables dynamic structural changes in tissue architecture.
Conclusions:
- Nanotechnology and 3D bioprinting are revolutionizing tissue engineering and regenerative medicine.
- 4D bioprinting introduces dynamic capabilities, allowing for adaptive tissue constructs.
- Future applications include bioactuation, biorobotics, and biosensing, expanding biomedical potential.

