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Poroid Neoplasms: A Clinicopathological Study of 13 Cases
Boubacar Efared1,2, Idrissa Boubacar2, Kadre Alio Ousmane Kadre1,3
1Faculty of Health Sciences, Abdou Moumouni University, Niamey, Niger.
Clinical Pathology (Thousand Oaks, Ventura County, Calif.)
|September 16, 2024
Summary
This study analyzed poroid neoplasms (PN), revealing that apocrine ductal differentiation, younger age, and non-palmoplantar locations are more common than previously thought. These findings challenge classical reports on PN clinicopathological features.
Area of Science:
- Dermatopathology
- Oncology
- Histopathology
Background:
- Poroid neoplasms (PN) are a diverse group of tumors originating from sweat glands and folliculo-sebaceous units.
- Histological classification and clinical presentation of PN can be challenging for clinicians and pathologists.
Purpose of the Study:
- To investigate and report the clinicopathological features of poroid neoplasms.
- To identify common characteristics of PN that may differ from classical descriptions.
Main Methods:
- A retrospective study was conducted on all registered cases of poroid neoplasms.
- Data were collected from the Pathology laboratory of Niamey National Hospital between February 2020 and February 2024.
Main Results:
- 13 cases of benign poroid neoplasms were identified, including classic poromas (76.9%), poroid hidradenomas (15.4%), and dermal duct tumors (7.7%).
- The mean age of affected individuals was 41.1 years, with a slight female predominance. Only 30.8% of cases were located in classical palmoplantar regions.
- Histological findings included clear cells (53.8%), apocrine ductal differentiation (46.2%), keratin horns (15.4%), squamous eddies (46.2%), melanin pigments (7.7%), and sebaceous differentiation (15.4%).
Conclusions:
- Apocrine ductal differentiation, younger patient age, and non-palmoplantar locations are frequently observed in poroid neoplasms.
- These findings contrast with traditional understandings of PN, highlighting the heterogeneity and varied presentation of these tumors.

