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Updated: Aug 11, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Adjuncts to annuloplasty in atrial functional mitral regurgitation
Anton Tomšič1, Tatiana Sequeira-Gross2, Christian Dumps3
1Department of Cardiothoracic Surgery Leiden University Medical Center Albinusdreef 2 2333 ZA Leiden Netherlands.
Insights
Atrial fibrillation can cause mitral regurgitation, often treated with ring annuloplasty. However, this repair
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomedical Engineering
Background:
- Atrial fibrillation (AF) is a common arrhythmia causing cardiac chamber dilation and functional mitral regurgitation (FMR).
- Heart failure with preserved ejection fraction (HFpEF) is frequently associated with AF and FMR, complicating disease progression.
- Current surgical repair for AF-related FMR involves true-sized ring annuloplasty, a standard but potentially suboptimal procedure.
Purpose of the Study:
- To evaluate the durability of current surgical repair strategies for atrial functional mitral regurgitation.
- To explore novel surgical approaches for improving the long-term efficacy of mitral valve repair in the context of atrial fibrillation.
Main Methods:
- Review of existing literature on surgical interventions for atrial functional mitral regurgitation.
- Analysis of recent studies investigating the long-term outcomes of ring annuloplasty.
- Exploration of combined mitral valve and left ventricular surgical strategies.
Main Results:
- While initial results of ring annuloplasty are favorable, long-term durability remains a concern.
- Evidence suggests that current repair methods may not fully address the underlying pathophysiology of AF-related FMR.
- Simultaneous targeting of the mitral valve and left ventricle shows promise for enhanced repair durability.
Conclusions:
- Refinement of surgical strategies is necessary to improve the durability of mitral valve repair in atrial fibrillation.
- Integrated approaches addressing both valvular and ventricular components may offer superior long-term outcomes for patients with AF-related FMR.
Abstract:
Atrial fibrillation is the most common cardiac arrhythmia, leading to progressive dilation of cardiac chambers, abnormal contraction patterns of the atria and ventricles and, potentially, atrioventricular valvular insufficiency. Moreover, heart failure with preserved ejection fraction is often present and closely intertwined with disease initiation and progression. Surgical valve repair with a true-sized ring annuloplasty is a well-established treatment option in atrial functional mitral regurgitation. While early results are good, recent studies have brought the durability of this repair approach into question, highlighting the need for further refinement of the surgical strategy. In particular, repair strategies that simultaneously target the mitral valve as well as the left ventricle could provide improved repair durability.
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