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Updated: Jun 13, 2025

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A Role for Germline Variants in Multiple Myeloma?

Brian A Walker1

  • 1Division of Hematology Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana.

Blood Cancer Discovery
|September 16, 2024
PubMed
Summary

Pathogenic germline variants (PGVs) in multiple myeloma patients are linked to DNA repair genes and a history of cancer. These patients may benefit from specific treatments, suggesting germline testing is valuable.

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