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INTDOSKIT: An R-Code for Calculation of Dose Coefficients and Studying Their Uncertainties
Bastian Breustedt1, Niranjan Chavan2, Thomas Makumbi2
1Karlsruhe Institute of Technology, Institute of Biomedical Engineering (IBT), Fritz-Haber-Weg 1, D-76131 Karlsruhe, Germany.
Health Physics
|September 16, 2024
Summary
A new R-code, INTDOSKIT, calculates time-dependent radiation dose distributions using International Commission on Radiological Protection (ICRP) models. This validated tool aids in assessing radiation exposure and supports uncertainty analysis in radiological protection.
Area of Science:
- Radiological Physics
- Computational Dosimetry
- Radiation Protection
Background:
- Accurate calculation of radiation dose is crucial for radiological protection.
- Existing models require robust computational tools for practical application.
- The International Commission on Radiological Protection (ICRP) provides reference models for dose assessment.
Purpose of the Study:
- To develop an R-code (INTDOSKIT) for calculating time-dependent activity distributions and doses based on ICRP reference models.
- To validate the developed code against established datasets and software.
- To demonstrate the code's capability in handling uncertainty and sensitivity analyses.
Main Methods:
- Development of a set of R functions and constants (INTDOSKIT).
- Implementation of ICRP reference models for activity distribution and decay.
- Validation using data from ICRP OIR Data Viewer and published decay chain models (e.g., 233Ra).
- Testing uncertainty and sensitivity analysis capabilities with a pilot study (241Am injection).
Main Results:
- The INTDOSKIT code successfully calculates time-dependent activity distributions and doses.
- Validation against reference data showed minimal deviations (few percent), attributed to rounding.
- The code accurately reproduced ICRP bioassay data and dose coefficients.
- Uncertainty analysis for 241Am injection yielded GSDs for dose coefficients consistent with literature.
Conclusions:
- INTDOSKIT provides a reliable and validated tool for dose assessment in radiological protection.
- The R-code facilitates the application of ICRP models and supports advanced analyses.
- The developed tool is suitable for calculating radiation doses, performing uncertainty, and sensitivity studies.
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