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Updated: Jun 13, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and

Ionel Sandovici1, Denise S Fernandez-Twinn2, Niamh Campbell3

  • 1Medical Research Council Metabolic Diseases Unit, Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK; Department of Obstetrics and Gynaecology and National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.

Cell Reports
|September 16, 2024
PubMed

Keywords:
CP: Developmental biologyGHIGF1IGF2adiposityfetal growth restrictiongenomic imprintinggrowth hormoneinsulin-like growth factor 1insulin-like growth factor 2metabolismmiR-483microRNAsmid-gestation lethality

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