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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Progestogen hypersensitivity: successful use of progesterone desensitisation and omalizumab to facilitate in vitro
Gary Xu1, Ramon Yuson1, Martina Rafferty1
1Department of Immunology, Concord Hospital, Sydney, New South Wales, Australia.
Abstract:
Hypersensitivity to exogenous or endogenous progesterone presents with a variety of clinical, usually cutaneous, manifestations. The condition can occur at any age during the reproductive years, causes debilitating symptoms and can impact the use of exogenous hormones. Management strategies include symptom control or hormonal manipulation via desensitisation. Strategic testing confirms the diagnosis, while targeted intervention can significantly and positively impact quality of life and further childbearing.
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