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Immunothrombosis: A bibliometric analysis from 2003 to 2023.

Mengyu Hou1, Jingxuan Wu, Jiangshuo Li

  • 1Department of Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

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This bibliometric study analyzes immunothrombosis research, revealing key topics like platelets, inflammation, and COVID-19. It highlights trends in understanding and treating thrombotic disorders.

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Area of Science:

  • Medical research
  • Biomedical science
  • Thrombosis research

Background:

  • Immunothrombosis is an intravascular innate immune response.
  • Dysregulated immunothrombosis contributes to thrombotic disorders.
  • COVID-19 has intensified research into immunothrombosis mechanisms and thrombotic events.

Purpose of the Study:

  • To conduct a bibliometric analysis of immunothrombosis research.
  • To identify current status, research hotspots, and future trends in the field.
  • To provide a comprehensive overview for researchers.

Main Methods:

  • Collected 495 papers from Web of Science (2003-2023).
  • Utilized VOSviewer and R package 'Bibliometrix' for analysis.
  • Analyzed publication metrics, keywords, and research trends.

Main Results:

  • Research spans 58 countries, involving 3287 authors and 1011 institutions.
  • Key topics include platelets, inflammation, neutrophil extracellular traps, Von Willebrand factor, and complement system.
  • Hotspots focus on COVID-19-related immunothrombosis and treatments for cardiovascular/cerebrovascular diseases.

Conclusions:

  • Bibliometric analysis offers a summary of immunothrombosis research achievements.
  • Identifies development trends and guides future research directions.
  • Provides a comprehensive understanding of the immunothrombosis research landscape.