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Primary Ewing Sarcoma in the Sphenoidal Sinus: A Case Report
Mohamed Amin Chaabouni1, Sirine Ayadi1, Yasmine Sghaier1
1ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Ear, Nose, & Throat Journal
|September 17, 2024
Summary
Ewing sarcoma (EWS) is a rare bone cancer. This case study details a challenging diagnosis and treatment of EWS in the paranasal sinuses, highlighting its rarity and complexity.
Area of Science:
- Oncology
- Head and Neck Surgery
- Pediatric Oncology
Background:
- Ewing sarcoma (EWS) is a rare malignant bone tumor predominantly affecting children and young adults.
- While typically found in long bones, EWS can rarely occur in the head and neck, including the paranasal sinuses.
Purpose of the Study:
- To present a challenging case of EWS in the paranasal sinuses.
- To discuss the diagnostic and management difficulties associated with this rare presentation.
Main Methods:
- Case report of a 45-year-old female with EWS of the sphenoidal and right nasal fossa.
- Surgical subtotal mass removal.
- Adjuvant radiotherapy and chemotherapy.
Main Results:
- Successful subtotal removal of the EWS mass.
- Completion of adjuvant radiotherapy and chemotherapy.
- Demonstration of a complex case requiring multidisciplinary management.
Conclusions:
- Ewing sarcoma in the paranasal sinuses is exceptionally rare.
- Diagnosis and management require a high index of suspicion and a tailored, multidisciplinary approach.
- This case underscores the challenges in treating rare head and neck malignancies.

