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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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Uncovering the coronavirus outbreak: present understanding and future research paths
Jayati Roy1, Arnab Banerjee1, Sandip Mukherjee1
1Department of Physiology (UG & PG), Serampore College, Serampore, West Bengal, India.
Journal of Basic and Clinical Physiology and Pharmacology
|September 17, 2024
Summary
This review covers severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathophysiology, transmission, and long-term COVID-19 health effects. Research and public health initiatives are crucial for managing the pandemic and its consequences.
Area of Science:
- Virology
- Immunology
- Epidemiology
Background:
- Discusses the pathophysiological mechanisms of SARS-CoV-2.
- Explains COVID-19's impact on multiple human body systems.
- Details viral entry mechanisms involving ACE2 and TMPRSS2.
Purpose of the Study:
- To review COVID-19 taxonomy, pathophysiology, symptomatology, and epidemiology.
- To analyze COVID-19's effects on respiratory, cardiovascular, and reproductive systems.
- To examine COVID-19 in India, including vaccine development and socioeconomic transmission factors.
Main Methods:
- Literature review of SARS-CoV-2.
- Analysis of pathophysiological mechanisms.
- Examination of epidemiological data and socioeconomic factors.
Main Results:
- COVID-19 manifests with diverse symptoms and post-acute issues affecting physical and mental health.
- The virus enters cells via ACE2 and TMPRSS2.
- Socioeconomic factors influence COVID-19 transmission rates in India.
Conclusions:
- Public health initiatives and vaccination programs are key to combating COVID-19.
- Further research is needed on long-term effects and treatments.
- Multidisciplinary collaboration is vital for pandemic prevention and public health protection.
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