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Area of Science:

  • Oncology
  • Health Services Research
  • Health Economics

Background:

  • Financial hardship is a dynamic concern for cancer patients.
  • Understanding longitudinal changes in financial hardship is crucial for effective patient support.

Purpose of the Study:

  • To assess longitudinal changes in financial hardship among patients with early-stage colorectal cancer.
  • Identify factors associated with financial hardship over time.

Main Methods:

  • Prospective longitudinal cohort study of 451 patients with stage I-III colorectal cancer.
  • Surveys administered at baseline, 3, 6, 12, and 24 months to measure cost-related nonadherence and material hardship.
  • Longitudinal multivariable logistic regression used to identify associated factors.

Main Results:

  • Material hardship decreased significantly over 24 months (57.6% to 35.0%, P < .001).
  • Cost-related nonadherence remained stable (8.8% to 9.2%, P = .84).
  • Factors like chemotherapy receipt, lower education, and safety-net hospital care were associated with increased hardship.

Conclusions:

  • Material hardship is prevalent but decreases over time in early-stage colorectal cancer patients.
  • Cost-related nonadherence remains a persistent issue.
  • Early and ongoing financial screening and intervention are recommended to mitigate patient financial burden.