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Updated: Jun 12, 2025
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Acute primary mesenteric venous thrombosis: A case report and literature review
Huiyan Lin1, Yunpeng Lou1, Ning Sha1
1Department of Intensive Care Unit, Navy No. 971 Hospital, Qingdao 266071, Shandong Province, China.
Introduction And Importance:
Mesenteric vein thrombosis (MVT) is a pathological condition characterized by the obstruction of blood flow caused by the formation of new thrombi in the mesenteric veins, resulting in the development of intestinal ischemia due to the absence of collateral circulation. The insidious onset, clinical manifestations and lack of specificity of laboratory tests are significant factors that impede the timely diagnosis of MVT in clinical setting.
Case Presentation:
This article critically examined the pathogenesis, diagnosis and treatment of a 60-year-old male patient with MVT, while also exploring the etiology, clinical manifestations, diagnostic approaches and management advancement with MVT.
Clinical Discussion:
We determined that CT angiography serves as a pivotal method for early detection of MVT. Proactive anticoagulation strategy utilizing unfractionated heparin or low molecular weight heparin can notably decrease the mortality rate of patients afflicted with MVT and enhance the clinical outcome.
Conclusion:
Surgery is generally not endorsed as the preferential therapeutic intervention for mesenteric venous thrombosis, barring patients with concurrent intestinal necrosis or perforation.
Insights
Mesenteric vein thrombosis (MVT) diagnosis is challenging due to non-specific symptoms. Early detection with CT angiography and prompt anticoagulation significantly improve patient outcomes for this condition.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Radiology
Background:
- Mesenteric vein thrombosis (MVT) obstructs blood flow, leading to intestinal ischemia.
- Delayed diagnosis of MVT is common due to insidious onset and non-specific clinical signs.
Observation:
- A 60-year-old male patient with MVT was analyzed for pathogenesis, diagnosis, and treatment.
- CT angiography was identified as crucial for early MVT detection.
Findings:
- Anticoagulation with unfractionated heparin or low molecular weight heparin reduces MVT mortality.
- Surgical intervention for MVT is typically reserved for cases with intestinal necrosis or perforation.
Implications:
- Timely diagnosis and anticoagulation are key to improving clinical outcomes in MVT.
- This case highlights the importance of advanced imaging and evidence-based treatment strategies for MVT.
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