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Updated: Jun 12, 2025

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
Published on: March 26, 2015
[Progress in the study of the correlation between dyslipidemia and demyelinating diseases of the nervous system]
1Department of Clinical Laboratory, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070,China Beijing Engineering Research Center of Immunological Reagents Clinical Research, Beijing 100070,China NMPA Key Laboratory for Quality Control of In Vitro Diagnostics, Beijing 100070, China.
Abstract:
Demyelinating disorders of the nervous system constitute a broad spectrum of neurological conditions characterized by the depletion of myelin sheaths accompanied by inflammatory cell infiltration, manifesting in either the central or peripheral nervous system. The former primarily encompasses conditions such as multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), while the latter is exemplified predominantly by Guillain-Barre syndrome (GBS). Recent investigations have revealed that dyslipidemia may be related to the occurrence and development of neurological demyelination, but there are fewer analyses and summaries of related advances in China. Consequently, this review aims to comprehensively outline advancements in research concerning the correlation between dyslipidemia and neurological demyelinating disordersand discusses in depth the interrelationship between dyslipidemia and neurological demyelinating diseases, so as to provide reference for the prevention and treatment of neurological demyelinating diseases.
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