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Iatrogenic pediatric unilateral vocal cord paralysis after cardiac surgery: a review
Amy Callaghan1, Hamdy El-Hakim1,2, Andre Isaac1,2
1Division of Pediatric Surgery, Department of Surgery, Stollery Children's Hospital, University of Alberta, Edmonton, AB, Canada.
Insights
Pediatric unilateral vocal cord paralysis (UVCP) lacks consistent diagnostic and treatment guidelines. More research is essential to understand its prevalence, natural history, and optimal surgical interventions for children.
Area of Science:
- Pediatric Otolaryngology
- Pediatric Pulmonology
- Pediatric Speech-Language Pathology
Background:
- Unilateral vocal cord paralysis (UVCP) affects multiple pediatric specialties.
- Iatrogenic injury is a common cause, but data on prevalence and symptom burden vary.
- Existing literature often conflates UVCP with bilateral vocal cord paralysis (BVCP).
Purpose of the Study:
- To review the current literature on pediatric UVCP.
- To identify inconsistencies in diagnosis, treatment, and outcomes.
- To highlight the need for further research.
Main Methods:
- Systematic reviews and meta-analyses were included.
- Retrospective and limited prospective studies were analyzed.
- Literature was assessed for data on prevalence, symptom burden, and treatment.
Main Results:
- Significant inconsistencies exist in the diagnosis and treatment of pediatric UVCP.
- Limited data available on the natural history and long-term outcomes.
- Lack of consensus on objective/subjective measurements and surgical intervention indications.
Conclusions:
- The current literature on pediatric UVCP is inconsistent and lacks comprehensive data.
- Further research is crucial to establish prevalence, natural history, and evidence-based treatment guidelines.
- Improved understanding is needed for surgical interventions like thyroplasty, injection medialization, and nerve reinnervation.
Abstract:
Unilateral vocal cord paralysis (UVCP) is a growing area of research in pediatrics as it spans across many specialties including otolaryngology, cardiology, general surgery, respirology, and speech language pathology. Iatrogenic injury is the most common cause of UVCP, however there is a wide range of data reporting the prevalence, symptom burden, and best treatment practice for this condition. The literature included systematic reviews and meta-analyses, retrospective studies and limited prospective studies. Overall, the literature lacked consistency in the diagnosis, treatment, and long-term outcomes of patients with UVCP. Many articles conflated bilateral vocal cord paralysis (BVCP) with UVCP and had limited data on the natural history of the condition. There was no consensus on objective and subjective measurements to evaluate the condition or best indications for requiring surgical intervention. Thyroplasty, injection medialization (IM) and recurrent laryngeal nerve reinnervation (RLNR) were the reported surgical interventions used to treat UVCP, however there was limited data on short and long-term surgical outcomes in children. More research is needed to determine the true prevalence, natural history, indications for surgical intervention and long-term outcomes for pediatric patients with this condition.
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