Related Experiment Video
Updated: Jun 12, 2025

Synthesis of an Intein-mediated Artificial Protein Hydrogel
Published on: January 27, 2014
Exploring the gelation and AIE properties of a tripodal acylhydrazone-based probe: turn-on Zn(II) sensing in HEPES
1Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India. gdas@iitg.ac.in.
Abstract:
Two C3-symmetric acylhydrazone-based AIE active probes, TRI-QUI and TRI-NAP, were synthesized with different peripheral substituents. The probe containing a quinoline moiety in the periphery displayed a selective turn-on response towards Zn2+ in HEPES buffer, with a calculated detection limit of 6.45 μM. The probe TRI-QUI was also identified as a supergelator as it formed a gel in DMSO-H2O (2 : 3, v/v) with a minimum gelation concentration of 0.5 mg mL-1. The gelator could interact with various metal ions or anions in the gel phase. Furthermore, the gelator could encapsulate small molecules like methyl orange and bromophenol blue, making the probe a multifunctional smart material.
Related Concept Videos
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Basicity of Heterocyclic Aromatic Amines
Diazonium Group Substitution: –OH and –H
Labeling DNA Probes
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Amines to Sulfonamides: The Hinsberg Test
Generally, a primary amine reacts with the Hinsberg reagent to produce an N-substituted benzenesulfonamide. The electron-withdrawing...
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism

![Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F55858.jpg&w=3840&q=50)