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Related Concept Videos

Dementia01:30

Dementia

102
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
102
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

451
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
451
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

170
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
170

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Systematic review and meta-analysis of associations between neuropsychiatric symptoms and amyloid, tau, neuronal, and glial biomarkers in young-onset dementias.

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Related Experiment Video

Updated: Jun 12, 2025

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

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Partners in progress: Advancing dementia research through collaboration.

John Roth1, Cathy Roth Oam1, Anita My Goh2

  • 1Professionals with Alzheimer's and related diseases (PALZ), Australia.

Dementia (London, England)
|September 18, 2024
PubMed
Summary
This summary is machine-generated.

Integrating the experiences of people with dementia, caregivers, and researchers is crucial for advancing dementia research. Collaborative, multi-voiced approaches can overcome traditional divides and foster innovation in dementia care and scientific understanding.

Keywords:
dementiainclusionrelationalrelationshipsresearch partnerships

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Area of Science:

  • Neuroscience and Gerontology
  • Patient-Centered Research
  • Qualitative Health Research

Background:

  • Dementia research often operates in silos, limiting collaboration between patients, caregivers, and scientists.
  • Traditional research models can create a divide between 'subjects' and 'experts', hindering relevance and innovation.
  • A holistic approach is needed to improve dementia research outcomes.

Purpose of the Study:

  • To bridge the divide between people with dementia, caregivers, and researchers.
  • To explore dementia research through the distinct lenses of patients, carers, and researchers.
  • To advocate for collaborative and relational approaches in dementia research.

Main Methods:

  • A tripartite exploration of dementia research.
  • Weaving together personal perspectives and insights from multiple stakeholders.
  • Utilizing a multi-voiced approach to capture diverse experiences.

Main Results:

  • Identified opportunities for collaboration across stakeholder groups.
  • Highlighted the limitations of traditional research dichotomies.
  • Demonstrated the potential of partnership and relational approaches.

Conclusions:

  • Convergence of lived experience, caregiver views, and researcher pursuits is essential for holistic dementia research.
  • Moving beyond the 'subject and expert' dichotomy fosters innovation and relevance.
  • Partnership and relational approaches unlock significant potential for improving dementia research and care.