Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

310
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
310
Organization of the Brain01:30

Organization of the Brain

745
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
745
Integration of Synaptic Events01:28

Integration of Synaptic Events

1.5K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability...
1.5K
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

2.4K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep...
2.4K
Neural Circuits01:25

Neural Circuits

1.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterogeneous functional state dynamics and its structural substrates in male individuals with autism spectrum disorder.

Molecular psychiatry·2026
Same author

Accelerated intermittent theta burst stimulation targeting personalized fronto-parietal control network improves core symptoms of autism spectrum disorder: a double-blind, randomized controlled trial.

Molecular psychiatry·2026
Same author

Linking changes in sulcal morphometry to cognitive development from childhood to adolescence.

Communications biology·2026
Same author

Spatiotemporal dynamics of the human cortical functional hierarchy across the lifespan.

Nature communications·2026
Same author

Personalized functional topography-based multisite brain age prediction modeling reveals divergent neurodevelopment in major depression.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

In Situ Room-Temperature Spontaneous Gelation Coupled with Asymmetric Viologen for High-Performance Electrochromic Devices.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

The cell cloud: Adopting systems biology concepts in the era of single-cell immunology.

PLoS biology·2026
Same journal

Disinhibitory signaling enables flexible coding of top-down information in cortical networks.

PLoS biology·2026
Same journal

Correction: Cdc42 interacts with chaperone Ydj1 to enhance its stability and partitioning during asymmetric cell division and aging in yeast.

PLoS biology·2026
Same journal

Towards globally equitable bioinformatics adoption.

PLoS biology·2026
Same journal

The human claustrum supports cognitive networks for externally and internally driven task demands.

PLoS biology·2026
Same journal

Unusual decay: Recombination loss leads to splicing errors in green algae.

PLoS biology·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.0K

Functional network modules overlap and are linked to interindividual connectome differences during human brain

Tianyuan Lei1,2,3,4, Xuhong Liao5, Xinyuan Liang2,3,4

  • 1Department of Psychiatry, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Plos Biology
|September 18, 2024
PubMed
Summary
This summary is machine-generated.

Brain functional modules show overlapping development in children, with changes linked to brain structure. This reveals how brain connectivity matures and relates to gray and white matter development.

More Related Videos

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.2K
A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.2K

Related Experiment Videos

Last Updated: Jun 12, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.0K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.2K
A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.2K

Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Network Science

Background:

  • The human brain's functional connectome is modular and reorganizes during development.
  • Previous research overlooked the spatial overlap between functional brain modules.
  • The developmental trajectory of overlapping modules and their structural basis are unknown.

Purpose of the Study:

  • To investigate the maturation of overlapping functional modules in the developing brain.
  • To explore the relationship between the development of overlapping modules and brain structural features.
  • To understand the principles of human brain connectome development.

Main Methods:

  • Longitudinal multimodal MRI data (structural, functional, diffusion) from 305 children (6-14 years).
  • Edge-centric network model to identify overlapping functional modules.
  • Entropy measure to quantify nodal overlap in module affiliations.

Main Results:

  • Regionally heterogeneous overlap topography, with higher overlap in ventral attention, somatomotor, and subcortical regions.
  • Linear and spatially distinct developmental patterns of overlapping modules, with decreasing overlap in prefrontal cortex and increasing overlap in parietal and lateral prefrontal cortex.
  • Overlapping modular patterns correlated with chronological age and were predicted by gray matter morphology and white matter microstructure.

Conclusions:

  • The study reveals the maturation of overlapping functional modules in the developing human brain.
  • Developmental changes in overlapping modules are associated with underlying structural properties of gray and white matter.
  • Findings advance the understanding of brain connectome development and its structural substrates.