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Published on: February 16, 2011
Transient ischemic dilatation in cardiac amyloidosis
Bethlehem Mengesha1, Gary Small1, David Ian Paterson1
1Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Insights
Transient ischemic dilatation (TID) on myocardial perfusion imaging, typically seen in coronary artery disease, is now described in cardiac amyloidosis. This finding expands the understanding of cardiac amyloidosis presentation on perfusion scans.
Area of Science:
- Cardiology
- Nuclear Cardiology
- Cardiovascular Imaging
Background:
- Cardiac amyloidosis is characterized by myocardial perfusion abnormalities and altered myocardial blood flow.
- Transient ischemic dilatation (TID) on perfusion imaging is a known finding in conditions like coronary artery disease and hypertrophic cardiomyopathy.
- The occurrence of TID in cardiac amyloidosis has not been previously documented.
Observation:
- A case of cardiac amyloidosis was identified.
- The patient presented with findings of transient ischemic dilatation on myocardial perfusion imaging.
Findings:
- This case demonstrates transient ischemic dilatation in the context of cardiac amyloidosis.
- This represents a novel observation linking TID to cardiac amyloidosis.
Implications:
- The findings suggest that transient ischemic dilatation may be an underrecognized imaging finding in cardiac amyloidosis.
- This observation could prompt further investigation into the mechanisms underlying TID in cardiac amyloidosis.
- Clinicians should consider cardiac amyloidosis in the differential diagnosis for patients presenting with TID on myocardial perfusion imaging, particularly when other causes are less likely.
Abstract:
Myocardial perfusion abnormalities and altered myocardial blood flow have been described in cardiac amyloidosis. Transient ischemic dilatation (TID) on perfusion imaging has been seen in the presence of multivessel coronary artery disease (CAD), hypertrophic cardiomyopathy, significant LV systolic dysfunction and hypertensive cardiomyopathy. But to our knowledge this phenomenon has not been described in cardiac amyloidosis. We present a case of cardiac amyloidosis presenting with transient ischemic dilatation on myocardial perfusion imaging.
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