Transient ischemic dilatation in cardiac amyloidosis

Bethlehem Mengesha1, Gary Small1, David Ian Paterson1

  • 1Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Insights

Transient ischemic dilatation (TID) on myocardial perfusion imaging, typically seen in coronary artery disease, is now described in cardiac amyloidosis. This finding expands the understanding of cardiac amyloidosis presentation on perfusion scans.

Area of Science:

  • Cardiology
  • Nuclear Cardiology
  • Cardiovascular Imaging

Background:

  • Cardiac amyloidosis is characterized by myocardial perfusion abnormalities and altered myocardial blood flow.
  • Transient ischemic dilatation (TID) on perfusion imaging is a known finding in conditions like coronary artery disease and hypertrophic cardiomyopathy.
  • The occurrence of TID in cardiac amyloidosis has not been previously documented.

Observation:

  • A case of cardiac amyloidosis was identified.
  • The patient presented with findings of transient ischemic dilatation on myocardial perfusion imaging.

Findings:

  • This case demonstrates transient ischemic dilatation in the context of cardiac amyloidosis.
  • This represents a novel observation linking TID to cardiac amyloidosis.

Implications:

  • The findings suggest that transient ischemic dilatation may be an underrecognized imaging finding in cardiac amyloidosis.
  • This observation could prompt further investigation into the mechanisms underlying TID in cardiac amyloidosis.
  • Clinicians should consider cardiac amyloidosis in the differential diagnosis for patients presenting with TID on myocardial perfusion imaging, particularly when other causes are less likely.

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