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Published on: February 11, 2017
Outcomes after bidirectional cavopulmonary shunt with antegrade pulmonary blood flow in high-risk patients
Lea Behrend1,2,3, Thibault Schaeffer1,2,3, Takuya Osawa1,2,3
1Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Insights
Antegrade pulmonary blood flow (APBF) was used in 8% of high-risk patients undergoing bidirectional cavopulmonary shunt (BCPS). While hospital stay and mortality were higher, long-term survival was similar for patients with and without APBF.
Area of Science:
- Congenital Heart Surgery
- Pediatric Cardiology
- Cardiovascular Surgery
Background:
- Bidirectional cavopulmonary shunt (BCPS) is a staged surgical palliation for complex congenital heart disease.
- Antegrade pulmonary blood flow (APBF) is sometimes maintained during BCPS in high-risk patients.
- Indications and outcomes of APBF in BCPS require further evaluation.
Purpose of the Study:
- To evaluate the indications for maintaining antegrade pulmonary blood flow (APBF) during bidirectional cavopulmonary shunt (BCPS).
- To compare the outcomes of patients with and without APBF after BCPS.
Main Methods:
- Retrospective review of patients who underwent BCPS between 1997 and 2022.
- Identification of patients with and without APBF post-BCPS.
- Comparison of demographic data, indications for APBF, hospital course, and long-term survival.
Main Results:
- APBF was utilized in 8.2% of 461 patients, primarily for high pulmonary artery pressure, hypoxemia, or hypoplastic pulmonary arteries.
- Patients with APBF had longer hospital stays and higher in-hospital mortality.
- Hospital survivors with and without APBF demonstrated similar long-term survival after BCPS and subsequent total cavopulmonary connection (TCPC).
Conclusions:
- APBF is employed in a small subset of high-risk BCPS patients, often due to elevated preoperative pulmonary artery pressure.
- Despite increased initial morbidity, APBF does not appear to compromise long-term survival for hospital survivors.
- Maintaining APBF during BCPS may be a viable strategy for select high-risk pediatric cardiac surgery patients.
Objective:
We have left antegrade pulmonary blood flow (APBF) at bidirectional cavopulmonary shunt (BCPS) only for high-risk patients. This study evaluates the indication and the outcomes of patients with APBF, compared to those without APBF.
Methods:
Patients with APBF after BCPS were identified among patients who underwent BCPS between 1997 and 2022. Outcomes of patients with and without APBF after BCPS were compared.
Results:
APBF was open in 38 (8.2%) of 461 patients. Median age (7.7 versus 6.3 months, p = 0.55) and weight (5.6 versus 6.1 kg, p = 0.75) at BCPS were similar in both groups. The most frequent indication for APBF was high pulmonary artery pressure (PAP) in 14 patients, followed by hypoxaemia in 10, and hypoplastic left pulmonary artery in 8. The source of APBF was the pulmonary trunk in 10 patients and the aortopulmonary shunt in 28. Median hospital stay after BCPS was longer (22 versus 14 days, p = 0.018) and hospital mortality was higher (10.5 versus 2.1%, p = 0.003) in patients with APBF compared to those without APBF. However, 448 hospital survivors showed similar survival after discharge following BCPS (p = 0.224). Survival after total cavopulmonary connection (TCPC) was similar between the groups (p = 0.753), although patients with APBF were older at TCPC compared to those without (3.9 versus 2.2 years, p = 0.010).
Conclusion:
APBF was left in 8% following BCPS in high-risk patients, mainly due to preoperative high PAP. Hospital survivors after BCPS demonstrated comparable survival in patients with and without APBF. Adding APBF at BCPS might be a useful option for high-risk patients.
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