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Chronic Urticaria in Children: A Single-Center Retrospective Study From Turkey

Zeynep Topkarci1, Gizem Gökçedağ Ünsal2, Burçe Can Kuru3

  • 1Department of Dermatology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Clinical Pediatrics
|September 19, 2024
PubMed

Insights

Childhood chronic urticaria (CU) is often linked to infections, particularly dental issues. This study highlights that chronic spontaneous urticaria (CSU) is the most common form in children, increasing with age.

Area of Science:

  • Pediatrics
  • Dermatology
  • Epidemiology

Background:

  • Childhood chronic urticaria (CU) research is limited.
  • Understanding CU's epidemiology and causes in children is crucial.

Purpose of the Study:

  • To investigate epidemiological and etiological factors in pediatric CU patients.
  • To analyze demographic data, laboratory findings, and triggers for CU in children under 18.

Main Methods:

  • Retrospective evaluation of 124 pediatric CU patients.
  • Analysis of patient demographics, clinical presentation, and identified etiological factors.

Main Results:

  • Chronic spontaneous urticaria (CSU) affected 75% of patients; chronic inducible urticaria (CIU) affected 24.2%.
  • Infections, primarily dental problems (16.9%), were the leading cause (29.8%), followed by drugs (8%).
  • No cause was found in 56.5% of cases; angioedema occurred in 18.5%.

Conclusions:

  • Pediatric CU prevalence rises with age, with CSU being most common.
  • Infections, especially dental issues, are significant etiological factors in childhood CU.
  • Further research is needed to identify causes in a substantial portion of pediatric CU cases.

Keywords:
angioedemachildchronic urticariainfectionsurticaria

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