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Updated: Jun 12, 2025
08:05
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
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Acinetobacter pittii thrombophlebitis complicating cyanoacrylate closure procedure
Javier J Barranco-Trabi1, Kaushal Desai2, Daniel Chen2
1Department of Medicine, Tripler Army Medical Center and U.S. Department of Veterans Affairs, Honolulu, HI.
Journal of Vascular Surgery Cases and Innovative Techniques
|September 19, 2024
Summary
Cyanoacrylate closure (CAC) for venous disease can lead to rare infections. This case highlights Acinetobacter pittii phlebitis, requiring vein removal and antibiotics.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Medical Device Innovation
Background:
- Chronic venous disease impacts quality of life, with treatments like cyanoacrylate closure (CAC) gaining popularity for faster recovery.
- Common side effects of CAC include phlebitis, bruising, and dermatitis.
- The VenaSeal device is a commonly used system for CAC procedures.
Observation:
- A patient with diabetes developed phlebitis after a CAC procedure using the VenaSeal device.
- The phlebitis was caused by Acinetobacter pittii bacterial contamination.
- The infection necessitated surgical vein resection and extended antibiotic treatment.
Findings:
- Bacterial contamination of cyanoacrylate adhesive in veins presents a challenge due to biofilm formation.
- Antibiotics alone may be insufficient for treating these infections.
- Aggressive source control, including vein removal, might be essential.
Implications:
- This case underscores the risk of endovascular infection following CAC procedures.
- Physicians should consider bacterial contamination as a potential complication, especially in diabetic patients.
- Further research into preventing and managing infections associated with endovascular adhesives is warranted.
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