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MRI changes in cryptococcal meningoencephalitis exacerbated by antifungal treatment due to post-infectious

Kenji Ohira1, Yo Kawarada1, Ryoko Iwata1

  • 1Department of Radiology, Shin-Kuki General Hospital, , 418-1 Kamihayami, Kuki City, Saitama Prefecture 346-8530.

Radiology Case Reports
|September 19, 2024
PubMed

Insights

Post-infectious inflammatory response syndrome can mimic treatment failure in cryptococcal meningitis. Early recognition and corticosteroid therapy are crucial for improving patient outcomes in this challenging neurological condition.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Immunology

Background:

  • Cryptococcal meningitis is a significant cause of mortality and morbidity worldwide.
  • It is a common fungal meningitis in adults, presenting diagnostic challenges.
  • Post-infectious inflammatory response syndrome (PIIRS) can complicate treatment, leading to paradoxical worsening of symptoms.
Keywords:
Cryptococcal meningitisDiagnostic challengesFungal meningitisMRIPostinfectious inflammatory response syndrome

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