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Related Experiment Video

Updated: Jun 12, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

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Psoriatic Onycho-Pachydermo-Periostitis.

Susan Hesni1, Davoud Khodatars1, Richard Rees2

  • 1Department of Radiology, Imperial College Healthcare NHS Trust, London, UK.

Journal of Psoriasis and Psoriatic Arthritis
|September 19, 2024
PubMed
Summary
This summary is machine-generated.

Psoriatic onycho-pachydermo-periostitis (POPP) is a rare psoriatic arthritis variant. Early recognition of POPP

Keywords:
arthropathyinflammatoryonycholysisperiostitispsoriasispsoriatic

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Area of Science:

  • Rheumatology
  • Dermatology
  • Radiology

Background:

  • Psoriatic onycho-pachydermo-periostitis (POPP) is an under-recognized psoriatic arthritis variant.
  • It presents with onycholysis, soft tissue thickening, and periostitis, often affecting the digits.
  • Clinical presentation can mimic fungal infections, leading to diagnostic delays.

Purpose of the Study:

  • To outline the clinical presentation, imaging features, pathogenesis, and treatment of POPP.
  • To increase awareness of this rare condition among healthcare professionals.
  • To facilitate earlier diagnosis and appropriate management of POPP.

Main Methods:

  • Literature review of POPP cases and existing research.
  • Analysis of clinical and imaging findings associated with POPP.
  • Synthesis of current understanding regarding pathogenesis and treatment strategies.

Main Results:

  • POPP is characterized by a triad of nail changes, soft tissue swelling, and periostitis.
  • A 'drumstick' digit appearance is a common, painful presentation.
  • Misdiagnosis as fungal infection is frequent due to nail involvement.

Conclusions:

  • Increased awareness of POPP is crucial for timely diagnosis and treatment.
  • Early identification aids in managing indeterminate seronegative conditions.
  • Understanding POPP's features can prevent prolonged incorrect therapies.