Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stability of Conjugated Dienes01:28

Stability of Conjugated Dienes

3.3K
Introduction
A comparison of the enthalpies of hydrogenation of dienes reveals that conjugated dienes release less heat on hydrogenation, rendering them more stable than their nonconjugated analogs.
3.3K
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry01:29

Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry

4.6K
Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
4.6K
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction01:16

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

10.1K
The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
10.1K
Stability of Substituted Cyclohexanes02:30

Stability of Substituted Cyclohexanes

12.4K
This lesson discusses the stability of substituted cyclohexanes with a focus on energies of various conformers and the effect of 1,3-diaxial interactions.
The two chair conformations of cyclohexanes undergo rapid interconversion at room temperature. Both forms have identical energies and stabilities, each comprising equal amounts of the equilibrium mixture. Replacing a hydrogen atom with a functional group makes the two conformations energetically non-equivalent.
For example, in...
12.4K
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry01:28

Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

3.8K
The Diels–Alder reaction is one of the robust methods for synthesizing unsaturated six-membered rings. The reaction involves a concerted cyclic movement of six π electrons: four π electrons from the diene and two π electrons from the dienophile.
3.8K
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

347
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
347

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spin-Flip Upconversion Luminescence and Tunable Downshifting Near-Infrared Emissions via 4d-4f Interaction in Doped Halide Perovskite.

Angewandte Chemie (International ed. in English)·2026
Same author

A Dysprosium Complex with Two Quasi-Degenerate Easy Axes.

Inorganic chemistry·2025
Same author

Enhanced red-light-driven hydrogen evolution by a diplatinum photocatalyst by the larger wavefunction leakage of iodide coordinated to the platinum center.

Chemical science·2025
Same author

Exploring a New Family of (Phosphinochalcogenoyl)Europocenes for Magneto-Optical Thermometry.

Angewandte Chemie (International ed. in English)·2025
Same author

A Linear Dysprosium(II) Metallocene with a High Effective Energy Barrier and Magnetic Hysteresis up to 70 Kelvin.

Journal of the American Chemical Society·2025
Same author

Breakdown of broken-symmetry approach to exchange interaction.

The Journal of chemical physics·2025

Related Experiment Video

Updated: Jun 12, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

10.7K

Stabilizing an exotic dianionic tetrazine bridge in a Ln2 metallocene.

Niki Mavragani1, Alexandros A Kitos1, Akseli Mansikkamäki2

  • 1Department of Chemistry and Biomolecular Sciences, University of Ottawa ON K1N 6N5 Canada m.murugesu@uottawa.ca.

Chemical Science
|September 19, 2024
PubMed
Summary

Researchers stabilized a highly reactive dianionic tetrazine species using lanthanide ions. This breakthrough provides the first structural and physical characterization of the tetrazine dianion, opening new avenues in redox chemistry.

More Related Videos

Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene
09:45

Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene

Published on: March 20, 2017

10.3K
Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

7.4K

Related Experiment Videos

Last Updated: Jun 12, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

10.7K
Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene
09:45

Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene

Published on: March 20, 2017

10.3K
Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

7.4K

Area of Science:

  • Inorganic Chemistry
  • Organometallic Chemistry
  • Redox Chemistry

Background:

  • The 1,2,4,5-tetrazine (tz) ring exhibits unique electronic properties, leading to significant scientific interest.
  • Tetrazines are known for their coordination chemistry with metal ions and rich redox behavior, existing in dihydro, neutral, and radical anion forms.
  • Previous studies suggested the possibility of a tetrazine dianion, but its high reactivity prevented isolation and characterization.

Purpose of the Study:

  • To stabilize and characterize the elusive dianionic tetrazine species.
  • To explore the coordination chemistry of tetrazines with lanthanide ions.
  • To investigate the structural and electronic properties of the dianionic tetrazine ligand within lanthanocene complexes.

Main Methods:

  • Synthesis of dinuclear lanthanocene complexes under strictly anhydrous and inert conditions.
  • Utilized strong reducing agents and non-acidic solvents.
  • Employed lanthanide ions to coordinate with tetrazine nitrogen atoms, sterically protecting the dianion.

Main Results:

  • Successfully isolated and characterized three dinuclear metallocene complexes: [(Cp*2Ln)2(tz˙-)(THF)2](BPh4) and [(Cp*2Ln)2(tz2-)(THF)2]·2THF.
  • Demonstrated the stabilization of the tetrazine radical anion (tz˙-) in one complex and the dianionic tetrazine (tz2-) in others.
  • The dianionic tetrazine (tz2-) was confirmed as a closed-shell planar species with distinct structural features compared to other tetrazine forms.

Conclusions:

  • This work reports the first structurally and physically characterized complexes containing the dianionic tetrazine radical.
  • The coordination to lanthanide ions effectively stabilized the highly reactive tz2- ligand.
  • The findings offer new insights into the redox chemistry of tetrazines and their potential applications in molecular systems and extended networks.