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Updated: May 2, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Reference charts for fetal corpus callosum length in the early second trimester: a prospective cross-sectional study
Nizamettin Bozbay1, Merve Nur Taşpınar2, Aybike Tazegül Pekin2
1Department of Perinatology, Faculty of Medicine, Selcuk University, Konya, Turkey. dr.nizamettin.bozbay@gmail.com.
Objective:
This study aimed to establish normal reference ranges for fetal corpus callosum (CC) measured by prenatal ultrasonography (USG) between 16 and 25 weeks of gestation in healthy fetuses.
Material And Method:
A total of 809 fetuses in the second trimester were evaluated by transabdominal USG. All measurements were obtained by a single clinician.
Results:
Based on the correlation analysis, a significant positive correlation was found between gestational week and CC (r = 0.907, p < 0.001).
Conclusion:
We anticipate that the reference intervals obtained from healthy fetuses will help clinicians who are interested in neurosonography to detect CC abnormalities at an early stage.

