Increasing the reach: optimizing screening for atrial fibrillation-the STROKESTOP III study

Area of Science:

• Cardiology
• Public Health
• Preventive Medicine

Background:

• Atrial fibrillation (AF) is a common arrhythmia and a major risk factor for ischemic stroke.
• Undiagnosed AF, often asymptomatic, poses a significant public health challenge.
• Early detection and treatment of AF can prevent strokes and improve patient outcomes.

Purpose of the Study:

• To compare the participation rates of opportunistic screening versus population screening for atrial fibrillation.
• To determine if opportunistic screening is a more effective method for increasing AF screening participation.
• To inform strategies for improving early detection of AF in at-risk populations.

Main Methods:

• STROKESTOP III, a randomized prospective cohort study involving 2954 individuals aged 75-76.
• Comparison of population screening versus opportunistic screening methods across 16 primary care clinics.
• Use of handheld one-lead ECG devices for 30-second recordings, three times daily for two weeks.

Main Results:

• The study aims to determine the participation rate in opportunistic screening compared to population screening.
• Participants with detected AF will be referred for primary healthcare physician consultation and treatment.
• The primary objective is to evaluate the effectiveness of opportunistic screening in increasing participation.

Conclusions:

• The STROKESTOP III study will yield crucial data on screening method effectiveness for atrial fibrillation.
• Findings will guide the selection of optimal screening strategies to enhance participation.
• Improved participation in AF screening can lead to better stroke prevention and public health outcomes.