Response to the comments on "Cellular aggregation dictates universal spreading behaviour of a whole-blood drop on a paper strip"
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Updated: Jun 12, 2025

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation
Published on: June 4, 2015
Sampad Laha1, Shantimoy Kar2, Suman Chakraborty3
1Department of Mechanical Engineering, Indian Institute of Technology, Kharagpur 721302, India.
Abstract:
In 2023, we published a research article in the Journal of Colloidal and Interface Science, based on our experimental findings and substantiating scaling arguments leading to a simple theoretical insight on the effect of red blood cell (RBC) aggregation on the wicking behaviour of a finite volume of blood as it navigates through the porous passages of a paper matrix (Laha et al., 2023). Of late, we received comments from Li (2024), which offered certain suggestions regarding the possible improvement of the capillary bundle model as considered in our article for analyzing the transport of blood through the paper pores. Herein, we provide a detailed discussion on each of the points raised by Li (2024) and rationalize our views in further details in addition to the contents already provided in our concerned article.

