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Light-chain amyloidosis with dysphagia as the main symptom: a case report
Maomao Ai1, Tao Lin2, Ruoyu Guo2
1Department of Otorhinolaryngology and Head and Neck Surgery, Guangzhou Red Cross Hospital, 396 Tongfu Middle Road, Haizhu District, Guangzhou, Guangdong, China. maomao6678@126.com.
Background:
Immunoglobulin light-chain amyloidosis is a relatively rare condition with a worldwide incidence of 5.1-12.8 cases per million person-years (Baker, 2022). It is characterized by a clonal population of immunoglobulin-secreting cells that produce a monoclonal light chain of κ or λ type as either an intact molecule or a fragment.
Case Presentation:
A 69-year-old East Asian (Chinese) male patient who presented with progressive dysphagia visited multiple hospitals repeatedly for more than 2 years and was finally diagnosed with immunoglobulin light-chain amyloidosis.
Conclusions:
Otolaryngologists should consider immunoglobulin light-chain amyloidosis when encountering suspicious clinical manifestations and intervene early to avoid misdiagnosis.
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