Static and temporal dynamic alterations of regional homogeneity in chronic insomnia: a resting-state fMRI study
Xiaoxin Chen1, Wenzheng Zhang1, Maoyang Wang1
1Department of Radiology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, China.
Abstract:
To explore brain function alterations in chronic insomnia (CI). 65 CI patients and 48 healthy controls were included to analyze abnormal alterations in brain spontaneous activity using static regional homogeneity (sReHo) and dynamic regional homogeneity (dReHo) methods. CI patients focused on decreased sReHo in bilateral lingual gyrus, bilateral middle occipital gyrus, bilateral inferior occipital gyrus and right superior occipital gyrus; decreased dReHo in bilateral superior occipital gyrus, bilateral cortical area around the talus fissure, and right middle occipital gyrus. CI patients exhibit abnormal activity in multiple brain regions, which can reflect the sleep quality index.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s41105-024-00541-0.
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