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Related Experiment Video

Updated: Jun 12, 2025

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
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Optimized needle configuration for operational seed (ONCOSEED) efficiency and deployment for prostate seed implants.

Siddhant Sen1, Ethan Stolen2, Jaehee Chun3

  • 1Department of Psychology, University of Illinois Urbana-Champaign, Champaign, IL, United States.

Technical Innovations & Patient Support in Radiation Oncology
|September 20, 2024
PubMed
Summary

ONCOSEED software significantly speeds up prostate cancer brachytherapy adjustments. It optimizes needle and seed configurations, reducing planning time by 28x compared to manual methods for adaptive brachytherapy.

Keywords:
BrachytherapyLDRNeedle configurationProstate seed implantSeed loading

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Area of Science:

  • Oncology
  • Medical Physics
  • Radiotherapy

Background:

  • Anatomical changes between prostate cancer brachytherapy planning and implantation necessitate adjustments to seed and needle configurations.
  • Current manual workflows for adapting treatment plans are time-consuming and resource-intensive.
  • There is a need for efficient tools to streamline configuration adjustments in low dose rate brachytherapy.

Purpose of the Study:

  • To introduce and evaluate ONCOSEED software for optimizing needle and seed adjustments in low dose rate brachytherapy.
  • To compare the efficiency of ONCOSEED against manual methods for adapting treatment plans.

Main Methods:

  • ONCOSEED software was developed to extract data from VariSeed treatment plans and calculate a labor score (LScore).
  • A case study involving three simulated VariSeed treatment plans was conducted.
  • The time taken by ONCOSEED to generate treatment plan adjustments was compared to manual annotation methods.

Main Results:

  • ONCOSEED demonstrated an average time saving of 28 times compared to manual workflow generation.
  • The software effectively optimizes adjustments to needle configurations for brachytherapy.

Conclusions:

  • ONCOSEED significantly enhances the efficiency of seed replacement in low dose rate brachytherapy.
  • The software promotes the adoption of adaptive brachytherapy practices by streamlining treatment planning.
  • ONCOSEED offers a faster and more efficient solution for managing anatomical variations in prostate brachytherapy.