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Updated: Jun 12, 2025

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Uncovering the Complexity of Perinatal Polysubstance Use Disclosure Patterns on X: Mixed Methods Study.

Dezhi Wu1, Hannah Shead2, Yang Ren3

  • 1Department of Integrated Information Technology, University of South Carolina, Columbia, SC, United States.

Journal of Medical Internet Research
|September 20, 2024
PubMed
Summary
This summary is machine-generated.

Perinatal polysubstance use (PPU) discussions on X reveal negative sentiments and stigma. Alcohol and drug combinations are common, highlighting the need for improved public health support and policies for pregnant individuals.

Keywords:
Twitterperinatal carepolysubstance usepregnant careprenatal caresentiment analysissocial media

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Area of Science:

  • Public Health
  • Social Media Analysis
  • Perinatal Care

Background:

  • Polysubstance use (PPU) among pregnant women is prevalent, yet mechanisms and contexts remain unclear.
  • Social media platforms like X (formerly Twitter) offer abundant organic data on public opinion.
  • Integrating traditional research methods with natural language processing (NLP) can yield valuable public health insights.

Purpose of the Study:

  • To analyze trends and sentiments of PPU discussions on X from May 2019 to October 2021.
  • To identify distinct patterns in PPU-related tweets and their implications for perinatal care and policy.

Main Methods:

  • Extracted over 6 million tweets using X's API, focusing on prenatal health and substance use keywords.
  • Filtered for US-based tweets, resulting in 4848 PPU-related tweets for mixed-methods analysis.
  • Employed quantitative (frequency, trend, sentiment analysis) and qualitative (thematic content analysis of 500 tweets) approaches.

Main Results:

  • PPU tweets exhibited more negative sentiment (51.36%) compared to non-PPU tweets.
  • Paired polysubstance use, particularly alcohol and drugs, was most common (85.27%).
  • Key themes included lifestyle, social perceptions, legal issues, and public health concerns driving PPU.

Conclusions:

  • X discussions highlight significant stigma and legal ramifications surrounding perinatal PPU.
  • Public sentiment towards PPU is mixed, with a concerning normalization trend observed.
  • Findings offer crucial insights for public health practitioners and policymakers to enhance support for individuals with PPU.