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Venom-induced myocarditis: An unusual case attributable to Vipera aspis bite
Stefano Maffè1, Paola Paffoni1, Emanuela Facchini1
1Division of Cardiology, SS Trinita' Borgomanero Hospital, ASL NO, Novara, Italy.
Toxicon : Official Journal of the International Society on Toxinology
|September 20, 2024
Summary
Viper bites can cause rare but serious heart inflammation (myocarditis). Prompt antivenom administration is crucial for recovery, even in regions with infrequent snake bites.
Area of Science:
- Cardiology
- Toxicology
- Medical Emergencies
Background:
- Venomous snake bites are medical emergencies with potential for severe systemic effects.
- Cardiovascular complications, though uncommon, require early detection and management.
- Myocarditis following viper envenomation is exceptionally rare in human cases.
Observation:
- A 33-year-old reptile zoo keeper experienced a Vipera aspis bite, leading to angioedema, compartment syndrome, and severe hematologic abnormalities.
- The patient exhibited hemodynamic instability, ECG changes (ST depression), pericardial effusion, and elevated troponin T.
- Cardiac MRI confirmed intramyocardial edema and inflammation consistent with myocarditis.
Findings:
- This case presents documented viper bite-induced myocarditis in Europe, diagnosed via echocardiography and cardiac MRI.
- The patient's condition improved significantly following administration of antivenom.
- Diagnostic imaging revealed septal and anterior intramyocardial edema without late gadolinium enhancement.
Implications:
- Highlights the importance of recognizing rare cardiovascular complications, such as myocarditis, after snake envenomation.
- Emphasizes the critical role of prompt antivenom administration in managing severe viper bites.
- Underscores the need for vigilance regarding snakebite severity, irrespective of geographic latitude.
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