Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Indirect Motor Pathways01:22

Indirect Motor Pathways

1.4K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.4K
Muscle Coordination and Action01:24

Muscle Coordination and Action

1.4K
Muscle coordination is a complex and finely tuned process essential for smooth and purposeful movements like flexion, extension, adduction, abduction, and rotation. The human body orchestrates the actions of various muscles working in concert, each with a specific role. Four functional types describe how muscles work together: agonist, antagonist, synergist, and fixator.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement....
1.4K
Hierarchy of Motor Control01:18

Hierarchy of Motor Control

2.5K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
2.5K
Direct Motor Pathways01:11

Direct Motor Pathways

1.8K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
1.8K
Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

1.3K
Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
1.3K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

928
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
928

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization.

eLife·2026
Same author

Spatial and temporal modulation of intra-limb coordination in kinematic synergies during hindlimb split-belt treadmill walking in rats.

Scientific reports·2026
Same author

Piperacillin/Tazobactam-Induced Granulomatous Interstitial Nephritis in a Patient with Squamous Cell Lung Cancer Successfully Managed with Chemoradiotherapy.

Internal medicine (Tokyo, Japan)·2026
Same author

Contribution of the anterior lateral motor cortex to predictive postural control in rats.

Scientific reports·2026
Same author

Anticipatory postural control emerges from a predictive and optimized strategy for movement preparation.

Communications biology·2026
Same author

Autogenic spinal excitatory circuit ensures skilled hand movements in primates.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Jun 12, 2025

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury
07:28

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury

Published on: March 24, 2023

2.7K

Interlimb coordination is not strictly controlled during walking.

Takahiro Arai1, Kaiichiro Ota2, Tetsuro Funato3

  • 1Center for Mathematical Science and Advanced Technology, Japan Agency for Marine-Earth Science and Technology, Yokohama, 236-0001, Japan.

Communications Biology
|September 20, 2024
PubMed
Summary
This summary is machine-generated.

Human gait control has a surprising "dead zone." Interlimb coordination isn't actively managed until leg movement deviates significantly, enhancing efficiency and maneuverability.

More Related Videos

3D Kinematic Gait Analysis for Preclinical Studies in Rodents
10:19

3D Kinematic Gait Analysis for Preclinical Studies in Rodents

Published on: August 3, 2019

10.6K
Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
08:19

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

Published on: January 15, 2016

8.8K

Related Experiment Videos

Last Updated: Jun 12, 2025

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury
07:28

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury

Published on: March 24, 2023

2.7K
3D Kinematic Gait Analysis for Preclinical Studies in Rodents
10:19

3D Kinematic Gait Analysis for Preclinical Studies in Rodents

Published on: August 3, 2019

10.6K
Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
08:19

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

Published on: January 15, 2016

8.8K

Area of Science:

  • Biomechanics
  • Neuroscience
  • Robotics

Background:

  • Human walking exhibits a stable antiphase relationship between left and right legs, crucial for interlimb coordination.
  • This coordination adapts to asymmetric conditions, but the underlying control mechanisms remain poorly understood.

Purpose of the Study:

  • To model the control of interlimb coordination during human walking.
  • To investigate the precise control mechanisms governing the relative phase between alternating legs.

Main Methods:

  • Utilized coupled oscillator models based on phase reduction theory.
  • Applied Bayesian inference methods to analyze walking data and derive control quantities.

Main Results:

  • Discovered a 'dead zone' in interlimb coordination control, where active control is absent below a specific deviation threshold from antiphase.
  • The relative phase is only actively adjusted when asymmetry exceeds this threshold.

Conclusions:

  • Human interlimb coordination control features a dead zone, potentially enhancing energy efficiency and maneuverability.
  • This finding offers new insights into the adaptive strategies of human gait control.