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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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  1. Home
  2. Research Domains
  3. Biomedical And Clinical Sciences
  4. Oncology And Carcinogenesis
  5. Predictive And Prognostic Markers
  6. Navigating Ankle Fracture Surgery In The Shadow Of Covid-19

Navigating Ankle Fracture Surgery in the Shadow of COVID-19

Justin P Chan1, Henry Hoang1, Amanda Anderson1

  • 1The Department of Orthopaedic Surgery, University of California Irvine, Orange, California.

Foot & Ankle Specialist
|September 21, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

Preoperative COVID-19 diagnosis before ankle fracture surgery did not significantly increase most postoperative complications. However, a higher risk of 30-day mortality was observed for patients diagnosed with COVID-19 within two weeks of surgery.

Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Public Health

Background:

  • Evaluating the impact of preoperative COVID-19 on surgical outcomes is crucial for patient management.
  • The National COVID-19 Cohort Collaborative (N3C) database provides a valuable resource for studying these effects.
  • Understanding COVID-19's influence on postoperative complications in orthopedic procedures is essential.

Purpose of the Study:

  • To assess the association between preoperative COVID-19 diagnosis and postoperative complications in ankle fracture surgery.
  • To investigate the influence of COVID-19 diagnosis timing relative to surgery on patient outcomes.
  • To identify potential risk factors and clinical outcomes affected by perioperative COVID-19 infection.

Main Methods:

  • A case-control study design was employed using the N3C database.
Keywords:
COVID-19ankle fractureoutcomesperi-operative

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  • The study included patients who underwent ankle fracture surgery, comparing those with and without a COVID-19 diagnosis within 12 weeks.
  • Outcomes included deep vein thrombosis, sepsis, surgical site infection, bleeding, acute kidney injury, and mortality, analyzed via multivariate logistic regression.
  • Main Results:

    • The COVID-19-positive group had slightly higher mean age and body mass index.
    • Frequencies of deep vein thrombosis and sepsis were slightly higher in the COVID-19-positive group but not statistically significant.
    • A significantly heightened risk of 30-day all-cause mortality was found for COVID-19 positivity within 0-2 weeks of surgery (AOR = 6.29, P = .003).

    Conclusions:

    • Preoperative COVID-19 diagnosis within 12 weeks of ankle fracture surgery was not significantly linked to most postoperative complications.
    • The timing of COVID-19 diagnosis relative to surgery is a critical factor, with early diagnosis posing a higher mortality risk.
    • While most complications were not significantly increased, the findings underscore the importance of considering COVID-19 status in surgical planning and patient care.
    postoperative complications