Trends in pre-biopsy MRI usage for prostate cancer detection, 2007-2022

Simon John Christoph Soerensen1,2, Shufeng Li3,4, Marvin E Langston5

  • 1Department of Urology, Stanford University School of Medicine, Stanford, CA, USA. simonjcs@stanford.edu.

PubMed
Abstract

Insights

Pre-biopsy MRI use for prostate cancer diagnosis has surged nationwide, yet significant disparities persist between urban and rural areas. Targeted interventions are needed to ensure equitable access to advanced imaging techniques.

Area of Science:

  • Urology
  • Radiology
  • Health Services Research

Background:

  • Clinical guidelines recommend magnetic resonance imaging (MRI) before prostate biopsy due to established benefits.
  • Understanding the real-world adoption of pre-biopsy MRI across the United States is crucial.

Purpose of the Study:

  • To analyze national trends in pre-biopsy pelvic MRI utilization for prostate cancer diagnostics.
  • To identify disparities in MRI adoption based on geographic location (urban vs. rural) and state.

Main Methods:

  • Analysis of 872,829 prostate biopsies in 726,663 men from 2007-2022 using the Merative™ Marketscan® databases.
  • Primary outcome: pre-biopsy pelvic MRI within 90 days of biopsy.
  • Statistical methods included descriptive statistics and generalized estimating equations to assess temporal, urban-rural, and state-level variations.

Main Results:

  • Pre-biopsy MRI utilization dramatically increased from 0.5% in 2007 to 35.5% in 2022.
  • Adoption was faster in urban areas (36.1% in 2022) compared to rural areas (28.3% in 2022).
  • Significant geographic disparities observed, with higher utilization in states like California, New York, and Minnesota, and lower rates in the Southeast and Mountain West.

Conclusions:

  • A significant shift towards MRI-guided approaches in prostate cancer diagnostics is evident, driven by updated guidelines and evidence.
  • Disparities in access to pre-biopsy MRI, especially in rural regions and specific geographic areas, necessitate targeted interventions.
  • Ensuring equitable access to advanced diagnostic techniques like MRI is essential for all patients.