Coronary Implications of COVID-19
Andreas S Triantafyllis1, Danai Sfantou1, Eleni Karapedi1
1Department of Cardiology, Asklepeion General Hospital, Athens, Greece.
Summary
COVID-19 (SARS-CoV-2) infection increases cardiovascular disease risk, including myocardial injury and acute coronary syndromes. Understanding these coronary implications is vital for timely diagnosis and treatment.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathophysiology
Background:
- SARS-CoV-2 infection is linked to a higher risk of cardiovascular diseases, such as myocardial injury, heart failure, and arrhythmias.
- The virus impacts the coronary arteries through mechanisms like thrombosis, endotheliitis, and vasculitis, increasing mortality risk.
Purpose of the Study:
- To review the pathophysiology and clinical spectrum of coronary implications associated with SARS-CoV-2 infection.
- To highlight the role of the angiotensin-converting enzyme 2 receptor in cardiovascular homeostasis during COVID-19.
Main Methods:
- Literature review of current research on COVID-19 and cardiovascular effects.
- Analysis of diagnostic tools including ECG, echocardiography, cardiac biomarkers, and coronary angiography.
- Overview of treatment strategies for various coronary complications.
Main Results:
- SARS-CoV-2 can cause acute coronary syndromes (ACS) via immune activation and coagulation dysregulation.
- Specific treatments vary, including revascularization for ACS, managing hypoxia/anemia for type 2 myocardial infarction, and vasodilators/antiplatelets for vasospasm/ectasia.
Conclusions:
- Accurate diagnosis and appropriate treatment of COVID-19-related coronary artery issues are crucial.
- Further research into the exact mechanisms of coronary involvement is needed for improved patient outcomes.
Keywords:
AneurysmAtherothrombosisCOVID-19Coronary arteryEndotheliitisMicrovascular dysfunctionMyocardial infarctionMyocardial injuryVasculitisVasospasmMore Related Videos
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