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Laryngeal chondrosarcoma, a 30-year series.
Patrícia Fernandes Lopes1, Joana Nascimento2, Gustavo Rocha3
1Hospital Central do Funchal, Ilha da Madeira, Portugal.
Acta Otorrinolaringologica Espanola
|September 22, 2024
Summary
Laryngeal chondrosarcoma, a rare cartilage tumor, is best treated with surgery. Close monitoring is crucial due to its tendency to recur, but outcomes are generally favorable.
Area of Science:
- Otorhinolaryngology
- Oncology
- Pathology
Background:
- Laryngeal chondrosarcoma is a rare tumor originating from cartilage, often affecting the cricoid cartilage.
- Its etiology remains largely unknown.
Purpose of the Study:
- To investigate the clinical presentation, treatment strategies, and patient outcomes of laryngeal chondrosarcoma.
- To analyze the long-term survival rates and recurrence patterns.
Main Methods:
- Retrospective analysis of 16 laryngeal chondrosarcoma cases from 1992 to 2022.
- Data collected on patient demographics, clinical presentation, surgical interventions, and follow-up outcomes.
Main Results:
- The study identified 16 cases, predominantly in males (two-thirds), with an average age of 59.6 years.
- Indolent dysphonia and/or dyspnea were common symptoms, with the cricoid cartilage's posterior arch being the most affected site.
- Surgery, primarily larynx microsurgery with debulking (47%) and partial laryngectomy (24%), was the primary treatment; adjuvant therapies were not used. Disease-specific survival rates at 1 and 5 years were 97% and 91%, respectively.
Conclusions:
- Laryngeal chondrosarcoma is effectively managed with surgical intervention, offering a generally favorable prognosis.
- The propensity for relapse necessitates vigilant long-term follow-up for optimal patient management.
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