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Factors Associated with Corticosteroid Adherence in Sarcoidosis.
Marc A Judson1,2, Wende Ouedraogo Ouedraogo3, Kenneth M Fish4
1Department of Medicine, Albany Medical Center, Albany, NY, USA. judsonm@amc.edu.
Lung
|September 22, 2024
Summary
Corticosteroid medication adherence in sarcoidosis patients is linked to their beliefs about medications and doctor communication, not demographics. Improving these factors can enhance treatment adherence for sarcoidosis management.
Area of Science:
- Pulmonary Medicine
- Pharmacology
- Patient-Reported Outcomes
Background:
- Sarcoidosis is a multisystem inflammatory disease often treated with corticosteroids.
- Corticosteroid medication adherence (CMA) is crucial for effective sarcoidosis management.
- Factors influencing CMA in sarcoidosis patients require further investigation.
Purpose of the Study:
- To measure CMA in sarcoidosis patients.
- To identify demographic, clinical, psychosocial, and relationship factors associated with CMA.
- To determine key predictors of CMA in this population.
Main Methods:
- 132 sarcoidosis patients receiving corticosteroids were enrolled.
- CMA was assessed using the Medication Adherence Response Scale-10 (MARS-10).
- Patient-reported outcomes (PROs) captured demographics, clinical data, beliefs, side-effects, and doctor-patient relationship quality.
Main Results:
- 75% of patients demonstrated good CMA (MARS-10 score ≥ 6).
- Demographic and most clinical factors showed no association with CMA.
- Better CMA was associated with positive medication beliefs and stronger doctor-patient communication.
Conclusions:
- CMA in sarcoidosis is primarily influenced by patient beliefs and physician communication.
- Demographic and socioeconomic factors do not significantly predict CMA.
- Interventions targeting patient beliefs and communication may improve corticosteroid adherence.
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