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Updated: Jun 12, 2025

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
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Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

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Higher risks of hyperopia, myopia, astigmatism, and strabismus in children with autism spectrum disorder: a

Yi-Lung Chen1, Cheng-Fang Yen2, Yu-Hung Lai3

  • 1Department of Psychology, Asia University, Taichung, Taiwan. Department of Healthcare Administration, Asia University, Taichung, Taiwan.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)
|September 23, 2024
PubMed

Insights

Children with autism spectrum disorder (ASD) have significantly higher risks for developing hyperopia, myopia, astigmatism, and strabismus. Early screening for these eye conditions in children with ASD is recommended.

Area of Science:

  • Ophthalmology
  • Neurodevelopmental Disorders
  • Pediatrics

Background:

  • Autism spectrum disorder (ASD) is a complex neurodevelopmental condition.
  • Ocular abnormalities are frequently observed in individuals with ASD.
  • The comparative risk of specific incident eye conditions in children with ASD is not well-established.

Purpose of the Study:

  • To compare the incidence risks of hyperopia, myopia, astigmatism, and strabismus.
  • To investigate these risks in children diagnosed with autism spectrum disorder (ASD) versus controls.

Main Methods:

  • Population-based cohort study utilizing the Taiwan Maternal and Child Health Database (TMCHD).
  • Included 20,688 children with ASD and 2,062,120 matched controls (born 2004-2017).
  • Cox proportional hazards regression models adjusted for sex, birth year, and gestational age.

Main Results:

  • Children with ASD exhibited elevated risks for incident hyperopia (aHR: 1.78), myopia (aHR: 1.27), astigmatism (aHR: 1.51), and strabismus (aHR: 2.18).
  • All identified risks were statistically significant (95% CIs did not include 1.0).

Conclusions:

  • Children with ASD demonstrate a significantly higher risk for developing common refractive errors and strabismus.
  • Routine ophthalmological screening is crucial for children diagnosed with ASD.
  • Further research is needed to understand the underlying mechanisms and the influence of ASD symptomology on eye conditions.
Abstract

Keywords:
Autism spectrum disorderastigmatismhyperopiamyopiastrabismus

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