Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

4.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.0K
Hypersensitivities01:30

Hypersensitivities

550
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
550
Allergic Drug Reactions01:27

Allergic Drug Reactions

818
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
818
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.7K
Allergic Reactions02:06

Allergic Reactions

27.3K
Overview
27.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eyelid Dermatitis: A 5-Year Retrospective Review from a Metropolitan Contact Dermatitis Clinic.

Dermatitis : contact, atopic, occupational, drug·2026
Same author

Assessment and Clinical Management of Patients With Atopic Dermatitis Undergoing Patch Testing: Recommendations From an International Electronic Delphi Consensus.

Dermatitis : contact, atopic, occupational, drug·2026
Same author

Digital Image Superimposition for Identifying Delayed Patch Test Reactions: A Clinical Pearl.

Dermatitis : contact, atopic, occupational, drug·2026
Same author

<i>Letter:</i> Formaldehyde Detected in Skin Glues by Chromotropic Acid Testing: A Possible Source of Allergic Contact Dermatitis.

Dermatitis : contact, atopic, occupational, drug·2026
Same author

To Avoid or Not to Avoid: Cross-Reactivity Between Fragrance and Common Botanicals.

Contact dermatitis·2026
Same author

High discrepancy rates in online allergen platforms: Implications for allergen avoidance.

Journal of the American Academy of Dermatology·2025

Related Experiment Video

Updated: Jun 12, 2025

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

3.4K

Allergic Contact Dermatitis in Skin of Color: A Retrospective Study from a Comprehensive Patch Testing Center.

Puneet Arora1,2, Caroline Brumley1,2, Kimberly Arrington1

  • 1From the Department of Dermatology, Park Nicollet Contact Dermatitis Clinic, HealthPartners, Minneapolis, MN, USA.

Dermatitis : Contact, Atopic, Occupational, Drug
|September 23, 2024
PubMed
Summary

Patch testing reveals common allergens like nickel and methylisothiazolinone (MI) affect all skin tones. However, specific allergens like acrylates and formaldehyde show higher prevalence in Asian and Hispanic patients, respectively.

More Related Videos

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.1K
Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.6K

Related Experiment Videos

Last Updated: Jun 12, 2025

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

3.4K
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.1K
Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.6K

Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Limited data exists on patch test results for diverse skin tones, including Hispanic, Asian, and Indigenous populations.
  • Understanding these differences is crucial for accurate diagnosis and management of allergic contact dermatitis.

Purpose of the Study:

  • To analyze and compare patch test results across different racial and ethnic groups at a single center.
  • To identify common allergens and highlight variations in allergic reactions among patients with skin of color.

Main Methods:

  • Retrospective analysis of 1389 patients undergoing comprehensive patch testing.
  • Stratification of results by self-reported race (White, Asian, Black, Hispanic, Indigenous).
  • Identification of common allergens and comparison of reaction frequencies between groups.

Main Results:

  • Nickel and methylisothiazolinone (MI) were common allergens across all groups.
  • Asian patients showed higher reactivity to acrylates and propylene glycol.
  • Black patients had increased sensitivity to dyes and rubber accelerators compared to White patients.

Conclusions:

  • While nickel and MI are universal allergens, specific allergens are disproportionately represented in certain racial/ethnic groups.
  • Cultural practices may influence allergen exposure and subsequent reactions.
  • Continued monitoring of patch testing trends in diverse populations is essential for dermatologists.