Related Experiment Video
Updated: Jun 12, 2025

12:18
LINE-1 Methylation Analysis in Mesenchymal Stem Cells Treated with Osteosarcoma-Derived Extracellular Vesicles
Published on: February 1, 2020
5.7K
Retraction: MicroRNA-103 promotes proliferation and inhibits apoptosis in spinal osteosarcoma cells by targeting p57
Oncology Research
|September 23, 2024
Abstract:
[This retracts the article DOI: 10.3727/096504017X15144741233346.].
Insights
This article has been retracted. The retraction notice does not provide specific reasons but indicates the original publication is no longer considered valid.
Area of Science:
- Scientific publishing
- Retraction notices
Context:
- The original article, identified by DOI 10.3727/096504017X15144741233346, has been retracted.
Purpose:
- To formally announce the retraction of a previously published scientific article.
Summary:
- A retraction notice has been issued for the article with DOI 10.3727/096504017X15144741233346.
- The specific reasons for this retraction are not detailed in the provided notice.
Impact:
- Invalidates the findings and conclusions of the retracted article.
- Maintains scientific integrity by correcting the scholarly record.
Related Concept Videos
MicroRNAs
3.0K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
3.0K
Abnormal Proliferation
4.5K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.5K
The Retinoblastoma Gene
4.1K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.1K

