Related Experiment Video
Updated: Jun 12, 2025

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
Research Trends of Rheumatoid Arthritis and Depression from 2019 to 2023: A Bibliometric Analysis
Yan Zhao1,2, Guang-Yao Chen3, Meng Fang1,2
1Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, People's Republic of China.
Background:
The co-occurrence of rheumatoid arthritis and depression typically exacerbates pain and leads to a range of adverse consequences, becoming a research hotspot in recent years. This study conducted the systematic retrieval of relevant articles within the past five years and employed bibliometric methods for scientometric analysis.
Methods:
Setting the keywords "Rheumatoid arthritis", "Depression" and "Depressive Disorder", relevant literature published between 2019 and 2023 was retrieved from the Web of Science database. Subsequently, the core information from the literature was subjected to visual analysis via CiteSpace software and bibliometric techniques.
Results:
A total of 974 articles related to rheumatoid arthritis and depression were identified through the search strategy, and 877 articles were retained for further analysis after duplicates. The United States (n=173), England (n=82), China (n=69), Canada (n=68), and Germany (n=54) ranked top five countries by publication count. The King's College London was the leading institution with the highest number of publications (n = 20). LANCET PSYCHIATRY was the most frequently cited journal (n = 72) despite having only one article. The top five authors with the largest number of publications include CHARLES N BERNSTEIN (n=14), RUTH ANN MARRIE (n=13), JOHN D FISK (n=12), CAROL A HITCHON (n=12) and SCOTT B PATTEN (n=12), and all these are based in Canada. The keywords with a centrality score exceeding 0.1 were depression, rheumatoid arthritis, symptom, quality of life, impact, fibromyalgia, disease activity, prevalence, inflammation, health, anxiety, pain, fatigue, disease, arthritis and disability.
Conclusion:
Related research between the co-occurrence of rheumatoid arthritis and depression was a persistent hotspot, but it still lacks of international collaboration and in-depth mechanistic exploration.
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
The JAK-STAT Signaling Pathway
Depression: Overview
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: MDD and Dysthymia
Connective Tissue Cell Types
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...

