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A novel organic chromo-fluorogenic optical sensor for detecting chromium ions.
Sayed M Saleh1, Reham Ali1, Azizah Algreiby1
1Department of Chemistry, College of Science, Qassim University, Buraidah, 51452, Saudi Arabia.
Heliyon
|September 23, 2024
Summary
A novel optical sensor film was developed for detecting trivalent chromium ions (Cr(III)). This sensor utilizes a diethyl 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarboxylate (3D) probe, offering high sensitivity and selectivity for essential micronutrient monitoring.
Area of Science:
- Analytical Chemistry
- Materials Science
- Environmental Science
Background:
- Trivalent chromium ion (Cr(III)) is an essential micronutrient vital for human physiological processes.
- Accurate sensing of Cr(III) is crucial for clinical analysis, environmental monitoring, and industrial applications.
- Existing methods for Cr(III) detection may lack the required sensitivity or selectivity for certain applications.
Purpose of the Study:
- To develop and design a novel, highly sensitive optical sensor film for the detection of Cr(III) ions.
- To investigate the sensing mechanism based on fluorescence enhancement upon Cr(III) complexation.
- To evaluate the sensor's performance characteristics, including sensitivity, selectivity, and detection limit.
Main Methods:
- A novel optical sensor film was fabricated using a diethyl 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarboxylate (3D) probe.
- The optical properties of the 3D probe and its complex with Cr(III) were characterized using fluorescence spectroscopy.
- The sensor's response was studied under physiological pH conditions (pH 7.4).
Main Results:
- The 3D probe exhibited distinct fluorescence emission at 460 nm upon excitation at 354 nm.
- Complexation with Cr(III) ions resulted in a 2:1 (metal:ligand) ratio, leading to fluorescence enhancement and a red-shift to 480 nm.
- The sensor demonstrated high sensitivity with a low detection limit of 0.37 × 10⁻³ μM, exceptional selectivity, and a binding constant of 1.40 × 10⁶ for Cr(III).
Conclusions:
- The developed optical sensor film based on the 3D probe offers a highly sensitive and selective method for Cr(III) detection.
- The fluorescence enhancement mechanism, attributed to the inhibition of photo-induced electron transfer (PET) by Cr(III)-3D complex formation, underpins the sensor's efficacy.
- This sensor provides a promising tool for Cr(III) monitoring in various applications, including environmental and clinical analyses.
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