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Tarlatamab for Large Cell Neuroendocrine Carcinoma in a Young Adult: A Case Report
Shetal A Patel1,2, Young Whang1,2, Chaely Medley2
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
JTO Clinical and Research Reports
|September 23, 2024
Abstract:
A 20-year-old man with metastatic large cell neuroendocrine carcinoma of the lung was treated with the delta-like ligand 3-targeting bispecific T cell engager, tarlatamab. Treatment was complicated by transient cytokine release syndrome but resulted in a partial response. Bispecific T cell engagers may offer a novel treatment approach for large cell neuroendocrine carcinoma of the lung.

