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Curative Surgery After Neoadjuvant Chemotherapy for Locally Advanced Sigmoid Colon Cancer With Extensive Abdominal
Hirofumi Suzumura1, Toshiaki Terauchi1, Seigo Yukisawa2
1Department of Surgery, Saiseikai Utsunomiya Hospital, Tochigi, JPN.
Neoadjuvant chemotherapy (NAC) with FOLFOX effectively shrank locally advanced colon cancer (LACC) with abdominal wall invasion, enabling curative surgery and reconstruction. This approach offers a promising treatment strategy for complex LACC cases.
Area of Science:
- Surgical Oncology
- Gastrointestinal Oncology
- Chemotherapy
Background:
- Locally advanced colon cancer (LACC) requires tailored treatment strategies for optimal prognosis.
- Extensive abdominal wall invasion in LACC presents challenges in achieving adequate surgical margins and defect repair.
- Neoadjuvant chemotherapy (NAC) has emerged as a promising option for LACC, potentially improving resectability and cure rates through tumor shrinkage.
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