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Dynamics of Splenic Transient Elastography in Patients With Alcohol Use Disorder
Mian B Khalid1, Hanna L Blaney1, Anusha Vittal1
1Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Introduction:
Splenic stiffness (SS) measurement (SSM) is an evolving noninvasive assessment to evaluate portal hypertension. Studies with respect to SSM in patients with alcohol use disorder are limited.
Methods:
We studied patients seeking treatment for alcohol use disorder in an inpatient treatment protocol at the National Institutes of Health and parsed SSM into 3 groups based on degree of change.
Results:
The improved SS group had statistically higher initial SSM and a nonstatistically increased liver stiffness measurement compared with others.
Discussion:
SS is dynamic in a subset of patients immediately after alcohol cessation, and improved SS is associated with a normalization of platelet count.
