Related Experiment Video
Updated: Jun 12, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
Molecular Characteristics and Expression of TKTL1 in Germ Cells: Implications for Nontumour Cell Research
Xiaole Yuan1, Huaiyan Kang2, Bo Liu1
1Shaanxi Province Engineering & Technology Research Center of Cashmere Goat, Yulin University, Yulin, Shaanxi, China.
Abstract:
TKTL1 is a crucial regulatory enzyme in the pentose phosphate pathway (PPP) and plays a significant role in energy synthesis. It is expressed in various tumour tissues, with its expression level closely associated with tumour invasion, metastasis and prognosis. Recent studies utilising proteomic analysis and other methods have highlighted the noteworthy expression of the TKTL1 gene in germ cells, particularly in spermatogonia and ovarian cells. Consequently, this article reviews the molecular characteristics of TKTL1 and its expression in germ cells to provide a reference for research on TKTL1 beyond tumour cells.
More Related Videos
Related Concept Videos
lncRNA - Long Non-coding RNAs
Non-LTR Retrotransposons

