Related Experiment Video
Updated: Jun 26, 2026

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
Published on: January 10, 2019
Evaluation of peripheral retinal degenerations using ultra-widefield swept source optical coherence tomography
Ayushi Agarwal1, Mousumi Banerjee1,2, Shorya Vardhan Azad1
1Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Purpose:
To describe the features of peripheral retinal degenerations using an Ultra-Widefield (UWF) Swept Source Optical Coherence Tomography (SS-OCT).
Method:
In this cross-sectional study done at a tertiary eye care centre in Northern India, peripheral retinal degenerations such as lattices, snail track lesion, paving stone, White With-Out Pressure(WWOP), micro-cystoid lesions, retinoschisis and other suspicious lesions were identified with clinical examination. Following clinical examination, these eyes with peripheral retinal degenerations underwent UWF OCT.
Results:
100 eyes with 14 peripheral lesions like lattices (31%), snail track lesions (10.4%), peripheral retinoschisis (7.5%), non-specific pigmented doubtful lesions (13.2%), WWOP (7.5%), paving stone (6.6%), peripheral retinal detachment (3.8%) along with CHRPE, micro-cystoid lesions and dark without pressure areas were identified. All the lesions could be imaged with the help of UWF-OCT. It significantly helped in improving diagnostic capability with early identification of specific structural features such as vitreoretinal attachment and traction, full-thickness hole or tear, and sub-retinal fluid which were not so evident on indirect ophthalmoscopy.
Conclusion:
UWF-OCT deepens our understanding of the structure of the retina and its associated peripheral pathologies, allowing early recognition of vision-threatening lesions that may influence clinical management.

