Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same authorSame journal

Incidence, predictors and outcomes following primary graft dysfunction after cardiac transplantation.

Transplant international : official journal of the European Society for Organ Transplantation·2026

Same author

Compassionate Use of Hypothermic Oxygenated Perfusion for Donor Hearts: Extending the Boundaries of Heart Recipient Complexity in Heart Transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026

Same author

Heart recipient outcomes following transplantation of donor hearts with impaired versus normal function: a study protocol for IMPROVED Heart, a prospective multicentre observational study.

BMJ open·2026

Same author

Geographical, institutional and workplace variability in genetic evaluation, screening practices, multidisciplinary care, and lung transplantation management for familial interstitial lung disease.

BMC pulmonary medicine·2026

Same author

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 2026 Annual Pediatric Heart Transplantation Report, Trends and Post-transplant Outcomes by Recipient Sex.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026

Same author

Menopausal hormone therapy prescription and ovary-sparing surgery in women with pre-menopausal endometrial cancer: a Swedish PremEnCa study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026

Search research articles

Related Experiment Video

Updated: Jun 12, 2025

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

Malignancies After Lung Transplantation.

Caroline Stenman¹, Andreas Wallinder^1,2, Erik Holmberg^3,4

¹Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.

Transplant International : Official Journal of the European Society for Organ Transplantation

|September 24, 2024

Summary

Lung transplantation recipients face a significantly higher risk of developing new cancers post-procedure. However, a history of cancer before lung transplant did not negatively impact long-term survival outcomes.

Keywords:

cancer cohort study epidemiology heart transplantation immunosuppression

More Related Videos

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Published on: January 19, 2019

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Related Experiment Videos

Last Updated: Jun 12, 2025

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Published on: January 19, 2019

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Area of Science:

Medical research
Oncology
Transplantation immunology

Background:

Lung transplantation (LTx) is a critical intervention for end-stage lung disease.
Understanding post-transplant cancer risk and outcomes in patients with prior cancer history is crucial.

Purpose of the Study:

To determine the incidence of malignancies after lung transplantation.
To evaluate the long-term survival of lung transplant recipients with a pre-transplant cancer diagnosis.

Main Methods:

Retrospective cohort study including 614 lung transplant recipients (1990-2016).
Cancer incidence determined via linkage with the Swedish Cancer Registry and Cause-of-Death registry.
Standardized Incidence Ratios (SIR) calculated to compare cancer risk with the general population.

Main Results:

159 malignancies diagnosed post-LTx, a 5.6-fold increased risk compared to the general population.
Most common post-LTx cancers: non-melanoma skin cancer (SIR 76.5), non-Hodgkin lymphoma (SIR 23.5), and lung cancer (SIR 8.89).
No significant difference in overall survival between recipients with and without prior cancer history (p=0.56).

Conclusions:

Lung transplant recipients have a substantially elevated risk of developing subsequent cancers.
A prior cancer diagnosis does not appear to adversely affect long-term survival in carefully selected lung transplant candidates.