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Homologous cell membrane-based hydrogel creates spatiotemporal niches to improve outcomes of dysregulated chronic
Yijuan Ding1, Qi Jia1, Ziwen Su1
1The M.O.E. Key Laboratory of Laboratory Medical Diagnostics, The College of Laboratory Medicine, Chongqing Medical University, #1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, China.
Materials Today. Bio
|September 24, 2024
Abstract:
The (M2M + TGF-β)@HAMA hydrogel dressing improves the outcomes of dysregulated chronic wound healing by protecting the open wound from repeated bacterial infections, reprogramming endogenous monocytes and M1 macrophages into an M2-phenotype, as well as enhancing fibroblastic proliferation and migration for matrix remodeling and granulation tissue formation.Image 1.

